Slow Cooker Cajun Chicken Alfredo – Creamy, Spicy, and Effortless

Why You’ll Love This Recipe

Slow Cooker Cajun Chicken Alfredo is the perfect blend of convenience and indulgence. Juicy chicken simmers low and slow with bold Cajun spices, garlic, and cream, creating a sauce that’s rich, flavorful, and perfectly spiced. Just before serving, tender pasta is tossed in to soak up all that creamy goodness, and Parmesan ties it all together with a nutty finish. Unlike traditional Alfredo, this version has a Cajun kick that keeps every bite exciting. The best part? The slow cooker does most of the work, making this dish perfect for busy weeknights or when you want to impress without spending hours in the kitchen. Comforting yet bold, it’s a restaurant-style meal made effortlessly at home.

Print

Ingredients

(Tip: You can find the complete list of ingredients and their measurements in the recipe card below.)

Chicken breasts or thighs – The main protein, tender and juicy after slow cooking.

Olive oil – Used to sear the chicken lightly before adding to the slow cooker (optional for more flavor).

Garlic – Adds savory depth and aroma to the sauce.

Cajun seasoning – The star flavor, giving the dish smoky heat and spice.

Paprika – Enhances the Cajun seasoning with warmth and color.

Salt and black pepper – Essential for balanced seasoning.

Chicken broth – Provides a savory base and keeps the sauce from being overly heavy.

Heavy cream – Makes the Alfredo sauce rich and velvety.

Parmesan cheese – Adds nutty sharpness and helps thicken the sauce.

Pasta (fettuccine or penne) – Classic Alfredo pasta, perfect for soaking up the creamy sauce.

Red pepper flakes – Optional, for those who enjoy extra heat.

Fresh parsley – A garnish that adds freshness and color to the finished dish.

Directions

Season the chicken with Cajun seasoning, paprika, salt, and pepper. For extra flavor, sear the chicken briefly in olive oil until golden on both sides, then transfer to the slow cooker.

Add garlic, chicken broth, and heavy cream to the slow cooker. Stir gently to combine. Cover and cook on low for 4–5 hours or on high for 2–3 hours, until the chicken is tender and fully cooked. Remove the chicken, slice or shred it, then return it to the slow cooker. Stir in Parmesan cheese until melted and smooth.

Cook the pasta separately according to package instructions until al dente. Drain, then toss the pasta directly into the slow cooker, coating it in the creamy Cajun Alfredo sauce. Adjust consistency with additional broth or cream if needed. Garnish with parsley and red pepper flakes before serving.

Servings and timing

This recipe makes 4–6 servings. Preparation takes 10 minutes, and slow cooking takes 4–5 hours on low or 2–3 hours on high. Including pasta cooking time, the total recipe time is about 5 hours on low or 3 hours on high.

Storage/reheating

Store leftovers in an airtight container in the refrigerator for up to 3 days. Reheat gently on the stovetop or in the microwave with a splash of cream or broth to loosen the sauce. This dish does not freeze well, as cream sauces can separate when thawed.

Variations and Customizations

Shrimp Alfredo – Swap chicken for shrimp and cook for less time, adding shrimp near the end to prevent overcooking.

Cheesy Upgrade – Add mozzarella or provolone for an even creamier sauce.

Vegetable Boost – Stir in spinach, mushrooms, or roasted bell peppers for extra texture and flavor.

Lighter Version – Replace heavy cream with half-and-half for a less rich sauce.

Gluten-Free Option – Use gluten-free pasta and ensure your Cajun seasoning is gluten-free.

Extra Spicy – Add cayenne pepper or hot sauce for a fiery kick.

Herb Twist – Mix in fresh basil or thyme alongside parsley for a more aromatic finish.

One-Pot Method – Stir uncooked pasta directly into the slow cooker during the last 30–40 minutes, adding extra broth if necessary.

FAQs

Can I use pre-cooked chicken?

Yes, add shredded rotisserie chicken in the last 30 minutes to heat through.

Does the pasta cook in the slow cooker?

It can, but cooking separately prevents overcooking and mushiness.

How spicy is this recipe?

It has a medium spice level from Cajun seasoning, but you can adjust by adding more or less.

Can I substitute milk for cream?

Whole milk works, but the sauce will be thinner and less rich.

What pasta works best?

Fettuccine, penne, or rigatoni are excellent choices for holding the sauce.

Can I make this dairy-free?

Yes, use coconut cream and a dairy-free Parmesan substitute.

How do I thicken the sauce?

Simmer uncovered for 10–15 minutes or add extra Parmesan cheese.

Can I double this recipe?

Yes, just make sure your slow cooker is large enough to handle the volume.

What side dishes pair well with this?

Garlic bread, Caesar salad, or roasted vegetables complement it perfectly.

Can I cook it on high instead of low?

Yes, 2–3 hours on high works well if you’re short on time.

Conclusion

Slow Cooker Cajun Chicken Alfredo is a rich, creamy, and spicy pasta dish that brings comfort and bold flavor with minimal effort. The slow cooker ensures the chicken stays tender and the sauce develops deep flavor, while Parmesan and cream make it luxuriously smooth. Perfect for weeknights, family meals, or gatherings, this dish delivers restaurant-worthy flavor straight from your slow cooker. Once you try it, it’s sure to become a repeat favorite.

Hungry for more?  Visit our website for full recipes and follow us on Pinterest for daily foodie inspo you’ll love to pin!